AHRI.PIP.RapidHIVTestImagesMetaData.2022.V1
AHRI.Population Intervention Programme:Images of point of care HIV tests 2017-2022
Name | Country code |
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South Africa | ZA |
As part of the ongoing individual health surveillance, Africa Health Research Institute (AHRI) collect point of care HIV test images from all consenting resident individuals aged 15 years and above. Operationally, these images are used by clinical research operations team as part of the quality assurance process to check if the HIV test results captured in the electronic data collection system are accurately entered and that patient referral is done appropriately for those needing HIV care. Scientifically, these images were also used in machine learning study conducted in collaboration with University College London which aimed at developing and piloting new mobile phone connected diagnostic tests for use in community settings. These tests used an application linked to a mobile camera to interpret the results. The performance of the tests was benchmarked to gold-standard diagnostic tests (Enzyme Linked ImmunoSorbent Assays (ELISA) and Polymerase Chain Reaction (PCR)) using patient samples (n=100).
For more, refer: Turbé, V., Herbst, C., Mngomezulu, T. et al. Deep learning of HIV field-based rapid tests. Nat Med 27, 1165-1170 (2021). <https>
Machine readable images of point of care (POC) HIV tests.
Photographs of individual test strip responses.
v1.0.0
Topic | Vocabulary | URI |
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HIV-1, Incidence, Machine Learning, Population Surveillance, Rural Population, HIV Infections, Africa | Africa Health Research Institute | www.ahri.org |
South Africa.
AHRI's Population Intervention Programme Study Area (PIPSA) situated in uMkhanyakude district KwaZulu-Natal province which is approximately 200km north of Durban. The area is approximately 845km2 in size and since 2017, the area has been expanded in to include the area which was formerly used for a cluster randomised trial on treatment as a prevention(TasP).
For more refer:
Dickman Gareta, Kathy Baisley, Thobeka Mngomezulu, Theresa Smit, Thandeka Khoza, Siyabonga Nxumalo, Jaco Dreyer, Sweetness Dube, Nomathamsanqa Majozi, Gregory Ording-Jesperson, Eugene Ehlers, Guy Harling, Maryam Shahmanesh, Mark Siedner, Willem Hanekom, Kobus Herbst, Cohort Profile Update: Africa Centre Demographic Information System (ACDIS) and population-based HIV survey, International Journal of Epidemiology, Volume 50, Issue 1, February 2021, Pages 33-34, <https>
Tanser F, Hosegood V, Bärnighausen T, Herbst K, Nyirenda M, Muhwava W, Newell C, Viljoen J, Mutevedzi T, Newell ML. Cohort Profile: Africa Centre Demographic Information System (ACDIS) and population-based HIV survey. Int J Epidemiol. 2008 Oct;37(5):956-62. doi: 10.1093/ije/dym211. Epub 2007 Nov 12. PMID: 17998242; PMCID: PMC2557060.
Iwuji CC, Orne-Gliemann J, Larmarange J, Balestre E, Thiebaut R, Tanser F, Okesola N, Makowa T, Dreyer J, Herbst K, McGrath N, Bärnighausen T, Boyer S, De Oliveira T, Rekacewicz C, Bazin B, Newell ML, Pillay D, Dabis F; ANRS 12249 TasP Study Group. Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial. Lancet HIV. 2018 Mar;5(3):e116-e125. doi: 10.1016/S2352-3018(17)30205-9. Epub 2017 Nov 30. PMID: 29199100.
All resident household members from AHRI's PIPSA aged 15 years and above and who gave informed consent for their rapid HIV test images to be photographed
Name | Affiliation |
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Kobus Herbst | AHRI |
Guy Harling | AHRI |
Mark Siedner | AHRI |
Willem Hanekom | AHRI |
Name |
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Africa Health Research Institute |
Name | Role |
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Welcome Trust | Funder |
SAPRIN | Funder |
Name | Affiliation | Role |
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Thobeka Mngomezulu | AHRI | Data collection |
Phumzile Dlamini | AHRI | Data collection |
Lindiwe Sithole | AHRI | Data collection |
Bonginkosi Ntimane | AHRI | Data quality |
Njabulo Myeni | AHRI | Data quality |
Eugene Ehlers | AHRI | Software Development |
Eugene Prenzler | AHRI | Data Analytics |
Brendan Gilbert | AHRI | IT infrastructure |
Sweetness Dube | AHRI | Data documentation |
Siyabonga Nxumalo | AHRI | Research Data management |
Dickman Gareta | AHRI | Research Data management |
Rapid HIV test image collection is integrated within the routine AHRI individual health surveillance
Start | End |
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2017-01-01 | 2022-12-05 |
The raw images have been stripped of the GPS coordinates and index data is completely anonymised.
Access to the data requires accurate completion of the online data access application form accessible on the AHRI Data repository(<https>). Data users are required to abide by the data use conditions stipulated on the application for access to the data. Failure to do so may result in their data access privileges revolved by the Data Custodian. In order to recognise the effort and intellectual contributions of AHRI investigators in producing and curating the data, users of AHRI data must acknowledge the source of the data and abide by the terms and conditions under which the data is accessed. All analytical datasets published on the AHRI Data Repository are assigned digital object identifier (DOIs) and the DOIs can be found on the Data Repository under Study Description tab - Access policy. AHRI data users are required to always cite the dataset using the DOI.
Due to the size of the zip file(>50GB), the images could not be published on the AHRI Data Repository. The images are therefore stored on the AHRI SharePoint. Users must request for access on the AHRI Data Repository by completing the online data request application form. Access to the SharePoint will only be granted to the data user once the Data Custodian has approved the user data request.
Herbst, K., Harling, G., Siedner, M., & Hanekom, W. (2023). Population Intervention Programme:Images of point of care HIV tests 2017-2022 [Data set]. Africa Health Research Institute. DOI:https://doi.org/10.23664/AHRI.PIP.RAPIDHIVTESTIMAGESMETADATA.2022
DDI.AHRI.PIP.RapidHIVTestImagesMetaData.2022.V1
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Africa Health Research Institute |