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The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa-2025

South Africa, 2004 - 2025
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Reference ID
IeDEA.2004-2025
Producer(s)
Dr Abraham Jacobus Herbst, Prof. Willem Hanekom, Prof. Janet Seeley, Prof. Maryam Shahmanesh, Dr. Guy Harling, Dr. Mark Siedner
Metadata
Documentation in PDF DDI/XML JSON
Created on
Oct 29, 2025
Last modified
Nov 06, 2025
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927
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  • Study Description
  • Data Dictionary
  • Downloads
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  • Identification
  • Version
  • Scope
  • Coverage
  • Producers and sponsors
  • Sampling
  • Data collection
  • Data processing
  • Data Access
  • Metadata production
  • Identification

    Survey ID number

    IeDEA.2004-2025

    Title

    The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa-2025

    Country
    Name Country code
    South Africa ZA
    Abstract

    TIER.net http://tier.net/ is an electronic patient management system that is used for monitoring and evaluation of HIV care and treatment programmes in government health facilities throughout South Africa. The system was designed as part of a 3-tier approach to implementing a full electronic medical records (EMR) system. This approach provides a flexible solution that allows facilities to transition towards EMR in stages, as their infrastructure improves, and resources become available. TIER.net http://tier.net/ forms the second tier, whereby patient's paper clinical records are entered into a non-networked computer at the health facility and transferred periodically to a central database.

    The TIER.net http://tier.net/ database contains information on clinic visit attendance, laboratory results and ART dispensing records for all patients on ART. The system was implemented in uMkhanyakude district in 2013; patient records from all visits before 2013 were back captured into the system. AHRI has a memorandum of agreement with the Department of Health to receive the TIER.net http://tier.net/ data for the 17 clinics in the Hlabisa health sub-district and Hlabisa hospital. A dedicated data entry clerk based in each clinic enters information from patients' paper clinical records into the TIER.net http://tier.net/ system after each patient visit. Laboratory results are manually entered into TIER.net http://tier.net/ after they have been received by the clinic (i.e. are not imported electronically from the National Health Laboratory Service (NHLS) system).
    Currently, pre-ART visits are not recorded in TIER.net http://tier.net/, although modules to capture HIV testing and pre-ART care may be implemented in the future.

    Kind of Data

    Clinical Data

    Unit of Analysis

    Individuals on ART at one of the 17 clinics from Hlabisa sub-district, uMkhanyakude district

    Version

    Version Description

    v4.0.0

    Scope

    Topics
    Topic Vocabulary URI
    HIV, Epidemiology, KwaZulu-Natal, Antiretroviral therapy, Hlabisa, Population Cohort Africa Health Research Institute www.ahri.org
    Keywords
    HIV, Epidemiology, KwaZulu-Natal, Antiretroviral therapy, Hlabisa, Population Cohort

    Coverage

    Geographic Coverage

    Hlabisa sub-district, KwaZulu-Natal, South Africa

    Universe

    Individuals from Hlabisa sub-district, KwaZulu-Natal, South Africa

    Producers and sponsors

    Primary investigators
    Name Affiliation
    Dr Abraham Jacobus Herbst Africa Health Research Institute
    Prof. Willem Hanekom Africa Health Research Institute
    Prof. Janet Seeley Africa Health Research Institute
    Prof. Maryam Shahmanesh Africa Health Research Institute
    Dr. Guy Harling Africa Health Research Institute
    Dr. Mark Siedner Africa Health Research Institute
    Producers
    Name
    Africa Health Research Institute
    Funding Agency/Sponsor
    Name Abbreviation Role
    Welcome Trust WT Funder
    DSI-MRC South African Population Research Infrastructure Network SAPRIN Funder
    South Africa Department of Health DoH Data Custodian
    Other Identifications/Acknowledgments
    Name Affiliation Role
    Dickman Gareta AHRI Research Data Management
    Kathy Baisley AHRI Statistics
    Eugene Prenzler AHRI IT infrastructure
    Brendan Gilbert AHRI IT infrastructure

    Sampling

    Sampling Procedure

    All individuals accessing ART treatment and care in the 17 clinics in Hlabisa sub-district, KwaZulu-Natal, South Africa

    Data collection

    Dates of Data Collection
    Start End
    2004-01-01 2025-09-20

    Data processing

    Data Editing

    Tier.Net data is processed and stored on servers under the physical control of AHRI until datasets are made available on the data repository. The data is de-identified and can then be downloaded for processing on the data user's computer.

    Data is stored on industry-standard relational databases with data integrity and user authentication for access control. Data is replicated on at least a daily basis to the Durban site of the Institution to provide secure offsite storage of data. Transactional logs are backed up every 30 minutes to enable recovery of data in the event of equipment failure.

    All users of the system are authenticated through individual passwords with minimum complexity and regular change rules (passwords must be at least eight digits, with a mix of small and capital letters, at least one numeric or non-alphabetic digit and changed at least every 45 days). AHRI uses industry standard malware and intrusion detection with at least annual penetration tests by a reputable outside security audit company.

    Data Access

    Access conditions

    Access to the data requires accurate completion of the online data access application form accessible on the AHRI Data repository(https://data.ahri.org/). Data users are required to abide by the data use conditions stipulated on the application for access to the data. Failure to do so may result in their data access privileges being revoked by the Data Custodian. In order to recognise the effort and intellectual contributions of AHRI investigators in producing and curating the data, users of AHRI data must acknowledge the source of the data and abide by the terms and conditions under which the data is accessed and must cite the dataset in publication using the citation provided as part of this documentation. All analytical datasets published on the AHRI Data Repository are assigned digital object identifier (DOIs) and the DOIs can be found on the Data Repository under Study Description tab - Access policy. AHRI data users are required to always cite the dataset using the relevant DOI.

    Citation requirements

    Herbst, A. J., Hanekom, W., Seeley, J., Shahmanesh, M., Harling, G., & Siedner, M. (2025). The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa-2025 [Data set]. Africa Health Research Institute.
    DOI: https://doi.org/10.23664/IEDEA.2004-2025

    Metadata production

    DDI Document ID

    DDI.IeDEA.2004-2025

    Producers
    Name Abbreviation
    Africa Health Research Institute AHRI
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