AHRI.PrEPImplementation.Clinical.Management
Thetha Nami ngithethe nawe (Let’s Talk): Clinic Management
| Name | Country code |
|---|---|
| South Africa | ZA |
Thetha Nami ngithethe nawe (Let's Talk): A stepped-wedge cluster randomised controlled trial of Social Mobilisation by peer navigators into community -based sexual health and HIV care (Including Pre-Exposure prophylaxis) to reduce sexually transmissible HIV amongst youth in rural KwaZulu-Natal, South Africa. “Thetha Nami ngithethe nawe” intervention is a tailored psychosocial support and social mobilisation into community-based SRH and differentiated HIV prevention, including PrEP and UTT. The intervention is provided by area-based peer navigators and adolescent- and youth-friendly nurse-led SRH mobile clinics that visit fixed sites across the clusters every 2 weeks.
Peer navigators deliver the following services to 15-30-year-olds: providing safe spaces to create an enabling environment; youth groups to mobilize young people; structured psychosocial and health needs assessment. Based on the needs assessment, they develop action plans that document the peer-led health promotion activities provided and planned. These include referral to mobile SRH and/or other services; individualized psychosocial support, provision of condoms, HIV self-tests and/or POCT, pregnancy tests; ART/PrEP pick-up through serostatus neutral adherence clubs with or without HIV self-test to support decentralised PrEP.
Main objective
To identify scalable and sustainable ways to stem the HIV epidemic and its negative impact on young people aged 15-30 in rural Kwa-Zulu Natal (KZN), South Africa through effective implementation of biosocial HIV prevention.
Specific objectives
Survey Data
Adolescents and young adults aged 15-30 attending sexual and reproductive health mobile clinics in rural Kwa-Zulu Natal (KZN).
V2.0.0
| Topic | Vocabulary | URI |
|---|---|---|
| Adolescents; young adults; HIV infections/prevention & control; South Africa/epidemiology; sexual health; PrEP; HIV prevention; clinical adherence; patient management. | Africa Health Research Institute | www.ahri.org |
Health and demographic surveillance site in the rural KwaZulu-Natal.
Thetha Nami ngithethe nawe is a cluster-randomized stepped-wedge trial (SWT) in 40 clusters within the health and demographic surveillance site. Clusters were randomized to receive the intervention in period 1 (early) or period 2 (delayed). Trained area-based peer navigators conducted needs assessments with youth aged 15-30 years to tailor health promotion, psychosocial support and referrals into nurse-led mobile SRH clinics.
The SRH mobile clinics visit the intervention clusters every 2 weeks. The clinics deliver nurse-led HIV testing, prevention and care including adolescent- and youth-friendly, gender neutral, HIV status neutral, individualized risk assessments for HIV care and PrEP, integrated with SRH services. During the SRH clinic appointment, participants receive counselling around sexual health, fertility intentions, contraception and HIV. All clinic attendees are offered pregnancy testing (if female), family planning support, choice of contraception, and syndromic management for STIs, and, if male, referral to voluntary medical male circumcision. Everyone is offered HIV counselling and POCT, and immediate initiation of ART if positive. All those who are HIV negative undergo screening for PrEP eligibility according to South African National guidelines. Those who are sexually active are also offered testing for STIs, including POCT for syphilis and hepatitis B (and vaccine if negative), self-taken vaginal swabs or urine tests for gonorrhoea and chlamydia, and treatment and partner notification if positive.
| Name | Affiliation |
|---|---|
| Dr Maryam, Shahmanesh | Africa Health Research Institute |
| Name |
|---|
| Africa Health Research Institute |
| Name | Abbreviation | Role |
|---|---|---|
| Bill and Melinda Gates foundation | BMG | Funder |
| Name | Affiliation | Role |
|---|---|---|
| Jaco Dreyer | Africa Health Research Institute | Data management, cleaning and analysis |
| Eva Ssozi | Africa Health Research Institute | Data management, cleaning and analysis |
All young people aged 15-30 years who are residing in intervention clusters and attend one of the study clinics following informed consent/assent.
| Start | End |
|---|---|
| 2022-06-06 | 2026-02-02 |
The data collected and captured on REDCap was uploaded to a MySQL database server within AHRI's secure server cluster.
The representative of the Receiving Organization agrees to comply with the following conditions:
Shahmanesh, M. (2026). Thetha Nami ngithethe nawe (Let’s Talk): Clinic Management [Data set]. Africa Health Research Institute.
DOI: https://doi.org/10.23664/AHRI.PREPIMPLEMENTATION.CLINICAL.MANAGEMENT
DDI.AHRI.PrEPImplementation.Clinical.Management
| Name | Abbreviation |
|---|---|
| Africa Health Research Institute | AHRI |