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Preferences for HIV pre-exposure prophylaxis delivery among young men with alcohol use in rural KwaZulu-Natal, South Africa: Discrete Choice Experiment and Demographic Data, 2025–2026

South Africa, 2025 - 2026
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Reference ID
AHRI.PrEParedForChange.Aim2.Demographic
Producer(s)
Alison Castle, Maryam Shahmanesh, Mark Siedner
Metadata
Documentation in PDF DDI/XML JSON
Created on
Mar 26, 2026
Last modified
Mar 26, 2026
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  • Identification
  • Version
  • Scope
  • Coverage
  • Producers and sponsors
  • Sampling
  • Data collection
  • Data processing
  • Data Access
  • Metadata production

    • Identification

    Survey ID number

    AHRI.PrEParedForChange.Aim2.Demographic
    Title

    Preferences for HIV pre-exposure prophylaxis delivery among young men with alcohol use in rural KwaZulu-Natal, South Africa: Discrete Choice Experiment and Demographic Data, 2025–2026
    Country
    Name Country code
    South Africa ZA
    Abstract

    This repository contains data from a discrete choice experiment (DCE) conducted among young men with alcohol use in rural KwaZulu-Natal, South Africa, to assess preferences for HIV prevention service delivery. Participants were recruited from a parent HIV prevention trial and completed a structured survey alongside a DCE consisting of nine choice tasks evaluating trade-offs across service location (soccer fields, shebeens, taxi ranks), service timing (weekdays, week evenings, weekends), and HIV prevention modality (event-driven oral PrEP [2-1-1], injectable PrEP, condoms-only).

    The dataset includes participant-level demographic and behavioral characteristics, discrete choice responses, and individual-level preference estimates (part-worth utilities) derived using hierarchical Bayesian modeling. These data enable analysis of preference heterogeneity, attribute importance, and subgroup differences in HIV prevention preferences.
    Kind of Data

    Demographic and behavioral data, choice responses from the DCE, individual-level preference utilities
    Unit of Analysis

    Individual study participant

    Version

    Version Description

    V1.0.0

    Scope

    Topics
    Topic Vocabulary URI
    HIV infection; pre-exposure prophylaxis; health services accessibility; health behavior; substance use Africa Health Research Institute www.ahri.org
    Keywords
    discrete choice experiment, PrEP preferences, young men, alcohol use, mobile HIV services, South Africa, implementation research

    Coverage

    Geographic Coverage

    The study was conducted within the Africa Health Research Institute (AHRI) Health and Demographic Surveillance System (HDSS) in uMkhanyakude district, KwaZulu-Natal, South Africa. This rural surveillance area is located approximately 200 km north of Durban and spans approximately 845 km². For more refer:

    1. Chidumwa G, Chimbindi N, Herbst C, et al. Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongst adolescents and young adults in rural KwaZulu-Natal: a 2 x 2 factorial randomised controlled trial. BMC Public Health 2022;22(1):454. DOI: 10.1186/s12889-022-12796-8.

    2. Castle AC, Busang J, Dreyer J, et al. Alcohol Use and the Pre-exposure Prophylaxis Continuum of Care Among Men in Rural South Africa: Results from a Longitudinal Study. AIDS Behav 2025. DOI: 10.1007/s10461-025-04694-y.
    Universe

    The study population consists of men aged 18 years and older residing within the AHRI HDSS in uMkhanyakude district, KwaZulu-Natal, South Africa. Participants were drawn from a parent HIV prevention trial and were eligible if they reported alcohol use, were living without HIV, and were sexually active during the parent trial.

    Producers and sponsors

    Primary investigators
    Name Affiliation
    Alison Castle AHRI; Massachusetts General Hospital
    Maryam Shahmanesh AHRI; University College London
    Mark Siedner AHRI; Massachusetts General Hospital
    Producers
    Name
    Africa Health Research Institute
    Funding Agency/Sponsor
    Name Abbreviation Role
    Massachusetts General Hospital Center for Global Health MGH CGH Funder
    National Institute of Mental Health NIMH Funder
    Bill & Melinda Gates Foundation Parent trial funding
    Wellcome Trust WT Core Funder
    Other Identifications/Acknowledgments
    Name Affiliation Role
    Nkosinathi Mthembu AHRI Data collection
    Lucky Nzimande AHRI Data collection
    Thenjiwe Ncube AHRI Data collection
    Bongani Nkosi AHRI Data collection
    Sweetness Dube AHRI Research Data management

    Sampling

    Sampling Procedure

    Participants were identified from a parent HIV prevention trial conducted within the AHRI Health and Demographic Surveillance System. Eligible participants were drawn from the trial registry and approached by trained research staff for participation in the discrete choice experiment. Recruitment was conducted in person within the study area, and participants completed the survey at a time and location convenient to them. A total of 185 participants completed the discrete choice experiment.

    Data collection

    Dates of Data Collection
    Start End
    2025-06-01 2026-01-31

    Data processing

    Data Editing

    1.1.1 Other Processing

    • DCE design generated using Sawtooth Lighthouse Studio using a D-efficient fractional factorial design
    • Data exported from REDCap and Sawtooth and cleaned in Stata
    • Hierarchical Bayesian models used to estimate individual-level preference utilities in Sawtooth Lighthouse Studio
    • Utilities were effects-coded and zero-centered within attributes
    • Dataset de-identified prior to repository submission

    Data Access

    Access conditions

    Access to the data requires accurate completion of the online data access application form accessible on the AHRI Data repository (https://data.ahri.org/). Data users are required to abide by the data use conditions stipulated on the application for access to the data. Failure to do so may result in their data access privileges revolved by the Data Custodian. In order to recognise the effort and intellectual contributions of AHRI investigators in producing and curating the data, users of AHRI data must acknowledge the source of the data and abide by the terms and conditions under which the data is accessed. All analytical datasets published on the AHRI Data Repository are assigned digital object identifier (DOIs) and the DOIs can be found on the Data Repository under Study Description tab - Access policy. AHRI data users are required to always cite the dataset using the DOI.
    Citation requirements

    Castle, A., Shahmanesh, M., & Siedner, M. (2026). Preferences for HIV pre-exposure prophylaxis delivery among young men with alcohol use in rural KwaZulu-Natal, South Africa: Discrete Choice Experiment and Demographic Data, 2025–2026 [Data set]. Africa Health Research Institute. DOI:https://doi.org/10.23664/AHRI.PREPAREDFORCHANGE.AIM2.DEMOGRAPHIC

    Metadata production

    DDI Document ID

    DDI.AHRI.PrEParedForChange.Aim2.Demographic
    Producers
    Name Abbreviation
    Africa Health Research Institute AHRI
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