Preferences for HIV pre-exposure prophylaxis delivery among young men with alcohol use in rural KwaZulu-Natal, South Africa: Discrete Choice Experiment and Demographic Data, 2025–2026

South Africa, 2025 - 2026

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Reference ID

AHRI.PrEParedForChange.Aim2.Demographic

Producer(s)

Alison Castle, Maryam Shahmanesh, Mark Siedner

Metadata

Documentation in PDF DDI/XML JSON

Created on

Mar 26, 2026

Last modified

Mar 26, 2026

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3650

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Identification

Survey ID number

AHRI.PrEParedForChange.Aim2.Demographic

Title

Preferences for HIV pre-exposure prophylaxis delivery among young men with alcohol use in rural KwaZulu-Natal, South Africa: Discrete Choice Experiment and Demographic Data, 2025–2026

Country

Name	Country code
South Africa	ZA

Abstract

This repository contains data from a discrete choice experiment (DCE) conducted among young men with alcohol use in rural KwaZulu-Natal, South Africa, to assess preferences for HIV prevention service delivery. Participants were recruited from a parent HIV prevention trial and completed a structured survey alongside a DCE consisting of nine choice tasks evaluating trade-offs across service location (soccer fields, shebeens, taxi ranks), service timing (weekdays, week evenings, weekends), and HIV prevention modality (event-driven oral PrEP [2-1-1], injectable PrEP, condoms-only).

The dataset includes participant-level demographic and behavioral characteristics, discrete choice responses, and individual-level preference estimates (part-worth utilities) derived using hierarchical Bayesian modeling. These data enable analysis of preference heterogeneity, attribute importance, and subgroup differences in HIV prevention preferences.

Kind of Data

Demographic and behavioral data, choice responses from the DCE, individual-level preference utilities

Unit of Analysis

Individual study participant

Version

Version Description

V1.0.0

Scope

Topics

Topic	Vocabulary	URI
HIV infection; pre-exposure prophylaxis; health services accessibility; health behavior; substance use	Africa Health Research Institute

Keywords

discrete choice experiment, PrEP preferences, young men, alcohol use, mobile HIV services, South Africa, implementation research

Coverage

Geographic Coverage

The study was conducted within the Africa Health Research Institute (AHRI) Health and Demographic Surveillance System (HDSS) in uMkhanyakude district, KwaZulu-Natal, South Africa. This rural surveillance area is located approximately 200 km north of Durban and spans approximately 845 km². For more refer:

1. Chidumwa G, Chimbindi N, Herbst C, et al. Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongst adolescents and young adults in rural KwaZulu-Natal: a 2 x 2 factorial randomised controlled trial. BMC Public Health 2022;22(1):454. DOI: 10.1186/s12889-022-12796-8.

2. Castle AC, Busang J, Dreyer J, et al. Alcohol Use and the Pre-exposure Prophylaxis Continuum of Care Among Men in Rural South Africa: Results from a Longitudinal Study. AIDS Behav 2025. DOI: 10.1007/s10461-025-04694-y.

Universe

The study population consists of men aged 18 years and older residing within the AHRI HDSS in uMkhanyakude district, KwaZulu-Natal, South Africa. Participants were drawn from a parent HIV prevention trial and were eligible if they reported alcohol use, were living without HIV, and were sexually active during the parent trial.

Producers and sponsors

Primary investigators

Name	Affiliation
Alison Castle	AHRI; Massachusetts General Hospital
Maryam Shahmanesh	AHRI; University College London
Mark Siedner	AHRI; Massachusetts General Hospital

Producers

Name
Africa Health Research Institute

Funding Agency/Sponsor

Name	Abbreviation	Role
Massachusetts General Hospital Center for Global Health	MGH CGH	Funder
National Institute of Mental Health	NIMH	Funder
Bill & Melinda Gates Foundation		Parent trial funding
Wellcome Trust	WT	Core Funder

Other Identifications/Acknowledgments

Name	Affiliation	Role
Nkosinathi Mthembu	AHRI	Data collection
Lucky Nzimande	AHRI	Data collection
Thenjiwe Ncube	AHRI	Data collection
Bongani Nkosi	AHRI	Data collection
Sweetness Dube	AHRI	Research Data management

Sampling

Sampling Procedure

Participants were identified from a parent HIV prevention trial conducted within the AHRI Health and Demographic Surveillance System. Eligible participants were drawn from the trial registry and approached by trained research staff for participation in the discrete choice experiment. Recruitment was conducted in person within the study area, and participants completed the survey at a time and location convenient to them. A total of 185 participants completed the discrete choice experiment.

Data collection

Dates of Data Collection

Start	End
2025-06-01	2026-01-31

Data processing

Data Editing

1.1.1 Other Processing

• DCE design generated using Sawtooth Lighthouse Studio using a D-efficient fractional factorial design
• Data exported from REDCap and Sawtooth and cleaned in Stata
• Hierarchical Bayesian models used to estimate individual-level preference utilities in Sawtooth Lighthouse Studio
• Utilities were effects-coded and zero-centered within attributes
• Dataset de-identified prior to repository submission

Access policy

Access conditions

Access to the data requires accurate completion of the online data access application form accessible on the AHRI Data repository (<https://data.ahri.org/>). Data users are required to abide by the data use conditions stipulated on the application for access to the data. Failure to do so may result in their data access privileges revolved by the Data Custodian. In order to recognise the effort and intellectual contributions of AHRI investigators in producing and curating the data, users of AHRI data must acknowledge the source of the data and abide by the terms and conditions under which the data is accessed. All analytical datasets published on the AHRI Data Repository are assigned digital object identifier (DOIs) and the DOIs can be found on the Data Repository under Study Description tab - Access policy. AHRI data users are required to always cite the dataset using the DOI.

Citation requirements

Castle, A., Shahmanesh, M., & Siedner, M. (2026). Preferences for HIV pre-exposure prophylaxis delivery among young men with alcohol use in rural KwaZulu-Natal, South Africa: Discrete Choice Experiment and Demographic Data, 2025–2026 [Data set]. Africa Health Research Institute. DOI:https://doi.org/10.23664/AHRI.PREPAREDFORCHANGE.AIM2.DEMOGRAPHIC

Metadata production

DDI Document ID

DDI.AHRI.PrEParedForChange.Aim2.Demographic

Producers

Name	Abbreviation
Africa Health Research Institute	AHRI

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