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AMETHIST RDS Clinical Data

South Africa, 2021 - 2023
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Reference ID
AHRI.AMETHIST.RDS.Clinical.Data
Producer(s)
Lusanda Mazibuko, Jaco Dreyer, Nompumelelo Mkwanazi, Prof. Maryam Shahmanesh
Metadata
Documentation in PDF DDI/XML JSON
Created on
May 25, 2026
Last modified
May 25, 2026
Page views
906
  • Study Description
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  • Identification

    Survey ID number

    AHRI.AMETHIST.RDS.Clinical.Data

    Title

    AMETHIST RDS Clinical Data

    Country
    Name Country code
    South Africa ZA
    Abstract

    AMETHIST is a study of Adapted Microplanning to Eliminate Transmissible HIV in Sex Transactions. In South Africa, the study examined how the AMETHIST model could be translated to a rural KwaZulu-Natal setting with less established clinical services for female sex workers. The work began with rapid participatory mapping to identify where, when and how sex work takes place, followed by a respondent-driven sampling bio-behavioural survey and clinical-service follow-up.

    Study Aim: To investigate translation of AMETHIST to rural KwaZulu-Natal, South Africa; to understand HIV risks and service needs among female sex workers; and to inform delivery, impact and cost-effectiveness of HIV prevention and related clinical services.

    Specific Objectives:

    • Describe the prevalence and patterns of sex work in the study setting, including how sex work is defined and organised.
    • Understand sexual risk across and along the sex-work life course, including transitions into and out of sex work.
    • Assess unmet health needs among female sex workers.
    • Determine how to deliver the AMETHIST intervention in rural KwaZulu-Natal, South Africa.
    Kind of Data

    Clinical Management, service follow-up, counselling, point-of-care testing, laboratory-review and visit-scheduling data linked to an RDS bio-behavioural study

    Unit of Analysis

    Participant visit/event record. A participant may contribute one initial visit and one or more follow-up visit records.

    Version

    Version Description

    v1.0.0

    Scope

    Topics
    Topic Vocabulary URI
    Adolescents; young adults; HIV infections/prevention & control; South Africa/epidemiology; sexual health; PrEP; HIV prevention; STI testing; clinical management. Africa Health Research Institute www.ahri.org
    Keywords
    Female sex workers, HIV prevention, sexual reproductive health, respondent-driven sampling, STI testing, PrEP, ART, clinical management, hard-to-reach populations.

    Coverage

    Geographic Coverage

    Africa Health Research Institute demographic surveillance area, rural KwaZulu-Natal, uMkhanyakude district.

    Universe

    Female sex workers aged 18 years and older living and/or working in the AHRI surveillance area. The clinical-management data include participants reached through the AMETHIST respondent-driven sampling study and recorded across clinical follow-up events.

    Producers and sponsors

    Primary investigators
    Name Affiliation
    Lusanda Mazibuko AHRI
    Jaco Dreyer AHRI
    Nompumelelo Mkwanazi AHRI
    Prof. Maryam Shahmanesh AHRI
    Producers
    Name
    Africa Health Research Institute
    Funding Agency/Sponsor
    Name Abbreviation Role
    Wellcome Trust Collaborative Award Wellcome Trust Funder

    Sampling

    Sampling Procedure

    The parent study used respondent-driven sampling following rapid participatory mapping and seed identification. The clinical-management file contains clinical and follow-up records generated during service delivery and study visits

    Data collection

    Dates of Data Collection
    Start End
    2021-11-30 2023-08-21

    Data processing

    Data Editing

    Variable descriptions below were generated systematically from the attached dataset.

    Data Access

    Access conditions

    Access to the data requires accurate completion of the online data access application form accessible on the AHRI Data repository(https://data.ahri.org/). Data users are required to abide by the data use conditions stipulated on the application for access to the data. Failure to do so may result in their data access privileges being revoked by the Data Custodian. In order to recognise the effort and intellectual contributions of AHRI investigators in producing and curating the data, users of AHRI data must acknowledge the source of the data and abide by the terms and conditions under which the data is accessed and must cite the dataset in publication using the citation provided as part of this documentation. All analytical datasets published on the AHRI Data Repository are assigned digital object identifier (DOIs) and the DOIs can be found on the Data Repository under Study Description tab - Access policy. AHRI data users are required to always cite the dataset using the relevant DOI.

    Citation requirements

    Mazibuko, L., Dreyer, J., Mkwanazi, N., & Shahmanesh, M. (2026). AMETHIST RDS Clinical Data [Data set]. Africa Health Research Institute.

    DOI: https://doi.org/10.23664/AHRI.AMETHIST.RDS.CLINICAL.DATA

    Metadata production

    DDI Document ID

    AHRI.AMETHIST.RDS.Clinical.Data

    Producers
    Name Abbreviation
    Africa Health Research Institute AHRI
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