Identification
Survey ID number
AHRI.TasP.DataEveryWhere.Dashboard.2016.v1
Title
Visualisation of sequence and demographic data to assist HIV surveillance in Northern KwaZulu-Natal: extending the TasP/iSense dashboard to include markers of HIV drug resistance mutations.
Country
| Name |
Country code |
|
South Africa |
ZA |
Abstract
This proposal aims to extend an existing collaboration between AHRI and UCL. As part of the iSense project, teams from AHRI and UCL have successfully developed a dashboard that integrates information from mobile computers used for TasP field visits with data from the clinics to display spatial coverage of homestead visits, highlighting those that require follow-up visits to ensure linkage to care. The dashboard provides a broad snapshot of the state of the study, spatially aggregating geographical zones in order to preserve the privacy of trial participants.
The aim of this proposal is to extend this framework to visualise presence and prevalence of drug resistance mutations (DRMs) within the study area. A higher prevalence of DRMs than expected may be linked to several factors, e.g. poor drug adherence, and thus of value to clinicians and healthcare workers in terms of focusing efforts and resource allocation.
Kind of Data
The existing dashboard is built on pseudonymised demographic data grouped into geographic hexagons. Within the PANGEA project, we have independently assembled HIV genomes from patient clinical samples and identified DRMs for each sample. To map the DRMs to each geographical hexagon, we require a lookup table to link the TasP/PANGEA IDs to hexagons.
Unit of Analysis
Each sample ID should be linked to a single hexagon where possible.