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    Home / Central Data Catalog / DREAMS / AHRI.FASTA.SEQUENCE.DATA.FOR.DREAMS.V3
DREAMS

Genomics data collected by DREAMS Nested- and Multilevel HIV Prevention.Version 03

South Africa, 2017 - 2020
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Reference ID
AHRI.Fasta.Sequence.Data.For.DREAMS.V3
Producer(s)
Dr Maryam, Shahmanesh, ,
Collections
Multilevel HIV Prevention
Metadata
Documentation in PDF DDI/XML JSON
Created on
Nov 11, 2020
Last modified
Nov 11, 2020
Page views
6660
Downloads
279
  • Study Description
  • Data Dictionary
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  • Identification
  • Version
  • Scope
  • Coverage
  • Producers and sponsors
  • Sampling
  • Data collection
  • Data processing
  • Data Access
  • Metadata production
  • Identification

    Survey ID number

    AHRI.Fasta.Sequence.Data.For.DREAMS.V3

    Title

    Genomics data collected by DREAMS Nested- and Multilevel HIV Prevention.Version 03

    Country
    Name Country code
    South Africa ZA
    Abstract

    The Genomics data was analysed from HIV Positive Dried Blood Spots (DBS) specimens collected during the data collection period for the DREAMS Nested- and Multilevel HIV Prevention projects.

    Kind of Data

    Genomics Data

    Unit of Analysis

    Specimen

    Version

    Version Description

    V3.0.0

    Scope

    Topics
    Topic Vocabulary URI
    Genomics data Africa Health Research Institute www.ahri.org
    Keywords
    DREAMS nested cohort; Genomics data; Multilevel HIV prevention

    Coverage

    Geographic Coverage

    Demographic surveillance area of the Africa Health Research Institute; KwaZulu-Natal, uMkhanyakude district.

    Universe

    DREAMS Nested cohort:
    A nested cohort of 800 AGYW will be followed prospectively at three time points over the two-year study period - baseline, 12 months and 24 months - at points closest aligned with periods before, during and after DREAMS implementation. In ACDIS cohorts of 400 girls aged 13-17 years and 400 young women aged 14-24 years will undergo informed consent, recruited undergo a baseline questionnaire and provide dried blood spot (DBS) sample for HSV2 and for the HIV testing, and then reviewed annually for the next two years.

    Multilevel HIV Prevention:
    Participants were randomly selected from a southern part of AHRI surveillance area, stratified by age, sex and week-block. A target sample size was 2500 males aged 13-35 and 500 females aged 24-29 years

    Producers and sponsors

    Primary investigators
    Name Affiliation
    Dr Maryam, Shahmanesh Africa Health Research Institute
    Producers
    Name
    Africa Health Research Institute
    Funding Agency/Sponsor
    Name Role
    Bill & Melinda Gates Foundation Impact Evaluation of PEPFAR funded DREAMS interventions
    South African Medical Research Council Genotyping funding source
    Other Identifications/Acknowledgments
    Name Affiliation Role
    Jaco Dreyer Africa Health Research Institute Data management
    Nondumiso Mthiyane Africa Health Research Institute Cleaning and analysis

    Sampling

    Sampling Procedure

    The type of sample and sample design used to select the survey respondents to represent the population. May include reference to the target sample size and the sampling fraction
    DREAMS: Adolescent girls and young women aged 13-24 years who were residents in the demographic surveillance area of the Africa Health Research Institute. A total of 3013 participants were randomly selected to obtain a target sample size of 800 after 2 years of follow-up, allowing for 40% non-contact/loss-to-follow-up. Sampling was stratified by age group and area (week-blocks).
    Multilevel: Participants were randomly selected from a southern part of AHRI surveillance area, stratified by age, sex and week-block. A target sample size was 2500 males aged 13-35 and 500 females aged 24-29 years.

    Data collection

    Dates of Data Collection
    Start End
    2017-05-03 2020-01-29

    Data processing

    Data Editing

    None

    Data Access

    Access conditions

    The representative of the Receiving Organization agrees to comply with the following conditions:

    1. Access to the restricted data will be limited to the Lead Researcher and other members of the research team listed in this request.
    2. Copies of the restricted data or any data created on the basis of the original data will not be copied or made available to anyone other than those mentioned in this Data Access Agreement, unless formally authorized by the Data Archive.
    3. The data will only be processed for the stated statistical and research purpose. They will be used for solely for reporting of aggregated information, and not for investigation of specific individuals or organizations. Data will not in any way be used for any administrative, proprietary or law enforcement purposes.
    4. The Lead Researcher must state if it is their intention to match the restricted microdata with any other micro-dataset. If any matching is to take place, details must be provided of the datasets to be matched and of the reasons for the matching. Any datasets created as a result of matching will be considered to be restricted and must comply with the terms of this Data Access Agreement.
    5. The Lead Researcher undertakes that no attempt will be made to identify any individual person, family, business, enterprise or organization. If such a unique disclosure is made inadvertently, no use will be made of the identity of any person or establishment discovered and full details will be reported to the Data Archive. The identification will not be revealed to any other person not included in the Data Access Agreement.
    6. The Lead Researcher will implement security measures to prevent unauthorized access to licensed microdata acquired from the Data Archive. The microdata must be destroyed upon the completion of this research, unless the Data Archive obtains satisfactory guarantee that the data can be secured and provides written authorization to the Receiving Organization to retain them. Destruction of the microdata will be confirmed in writing by the Lead Researcher to the Data Archive.
    7. Any books, articles, conference papers, theses, dissertations, reports, or other publications that employ data obtained from the Data Archive will cite the source of data in accordance with the citation requirement provided with the dataset.
    8. An electronic copy of all reports and publications based on the requested data will be sent to the Data Archive.
    9. The original collector of the data, the Data Archive, and the relevant funding agencies bear no responsibility for use of the data or for interpretations or inferences based upon such uses.
    10. This agreement will come into force on the date that approval is given for access to the restricted dataset and remain in force until the completion date of the project or an earlier date if the project is completed ahead of time.
    11. If there are any changes to the project specification, security arrangements, personnel or organization detailed in this application form, it is the responsibility of the Lead Researcher to seek the agreement of the Data Archive to these changes. Where there is a change to the employer organization of the Lead Researcher this will involve a new application being made and termination of the original project.
    12. Breaches of the agreement will be taken seriously and the Data Archive will take action against those responsible for the lapse if willful or accidental. Failure to comply with the directions of the Data Archive will be deemed to be a major breach of the agreement and may involve recourse to legal proceedings. The Data Archive will maintain and share with partner data archives a register of those individuals and organizations which are responsible for breaching the terms of the Data Access Agreement and will impose sanctions on release of future data to these parties.

    Metadata production

    DDI Document ID

    DDI.AHRI.Fasta.Sequence.Data.For.DREAMS.V3

    Producers
    Name
    Africa Health Research Institute
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