EVOLVE-HBV (Evaluation of Vukuzazi LiVEr disease - Hepatitis B): A retrospective serosurvey of Hepatitis B Virus (HBV) infection, exposure, and vaccine-mediated immunity using archived samples from the Vukuzazi Study (2018-2020).

South Africa, 2018 - 2020

Get Microdata

Reference ID

AHRI.EVOLVE.HBV

Producer(s)

Siyabonga Nxumalo, Lusanda Mazibuko, Nompumelelo Mkwanazi, Prof Philippa C Matthews, Prof Collins Iwuji, Dr Motswedi Anderson, Kathy Baisley, Gregory Ording-Jespersen, Mark Siedner, Emily Wong, Willem Hanekom, Vukuzazi Field Team, Sample Processing Unit, Khanyi Msomi, Theresa Smit, Dickman Gareta,

Metadata

Documentation in PDF DDI/XML JSON

Created on

Jul 14, 2026

Last modified

Jul 14, 2026

Page views

643

Downloads

2

Data file: vk_evolve

Cases:	2200
Variables:	295

Variables

individualid

iintid

sex

birthyear

hbvdob

HBV vaccine age epoch

educ_recoded

Education level

sescat

Socioeconomic status

drink3cat

smoke3cat

bmicat

hivstat

HIV status (ELISA)

onart

On ART (cascade)

vl_suppressed

Viral load <50 copies/mL (PLWH only)

hypertension

diabetic

hbsag_interpretation

HBsAg_Interpretation

hbsab_interpretation

HBsAb_Interpretation

anti_hbcii_interpretation

Anti_HBcII_Interpretation

hbsag_result

hbv_num

active_disease

HBsAg positive (qualitative)

hbv_active

HBsAg S/CO > 10 (sensitivity definition)

vax_med_immune

Vaccine-mediated immunity (HBsAb+ / others -)

hbvexpo_clear

Exposure & clearance (anti-HBc+ / HBsAg-)

susceptible

Susceptible (HBsAg-/anti-HBc-/anti-HBs-)

ipw_weights

totwt

box_no

position_no

label_id

text_id

processing_barcode

Processing_barcode

trackcare_barcode

TrackCare_Barcode

hbsab_result

anti_hbcii_result

Anti_HBcII_Result

dateofbirth

Individual's Date of Birth

mobileclinicvisitdate

Date of visit at the Vukuzazi mobile clinic

bmi

Body Mass Index

dateofdeath

died

clinic_tot1y

Number clinic visits in past year (ClinicLink)

clinic_1y

Any clinic visits in past year (ClinicLink)

hosp_tot1y

Number hospitalisations in past year (HIS)

hosp_1y

Hospitalised in past year (HIS)

consent_rdt

Ever consent to RDT in PIP (2017/2018)

ses_score

SES score (component 1)

kmtonearestclinic

Straight-line distance to clinic named in previous variable

studyoutcome

Individual study outcome

homesteadvisitdate

Date of visit at the homestead

ageatrecruitment

Age at recruitment

ageatrecruitmentcat

Age category at recruitment

ageatenrolment

Age at enrolment

ageatenrolmentcat

Age category at enrolment

hhintid

PIP unique household Id

bsintid

PIP unique bounded structure Id

episode

This episode number (first=1, last=Episodes)

episodes

Total number of episodes for individual

startdate

Start date of episode (inclusive)

enddate

End date of episode (inclusive)

resident

Whether individual is resident for duration of episode

education

Education status of individual during this episode

maritalstatus

Marital status of the individual during this episode

currentlyemployed

Employment status of the individual during this episode

visitdate

Vukuzazi camp visit date

currsmoker

Do you currently smoke any tobacco products, such as cigarettes, cigars or pipes

currsmokerdaily

Do you currently smoke tobacco products daily?

agestartedsmoking

How old were you when you first started smoking?

cursmokedur

Years smoking daily (current smokers)

agestartedsmokingunknown

Age started smoking unknown?

howlongstartedsmoking

Do you remember how long ago it was?

howlongstartedsmokingspecifiy

Could you specify long ago it was?

othertobaccospecify

Do you smoke Other products?

secagestartedsmoking

How old were you when you first started smoking (Age)?

secstartedsmokingmonths

Started smoking in months

secstartedsmokingweeks

Started smoking in weeks

manufacturedcigarettesdaily

On average, how many of the following products do you smoke each day/week?

manufacturedcigarettesweekly

On average, how many of the following products do you smoke each day/week?

handrolledcigarettesdaily

On average, how many of the following products do you smoke each day/week?

handrolledcigarettesweekly

On average, how many of the following products do you smoke each day/week?

pipedtobaccodaily

On average, how many of the following products do you smoke each day/week?

pipedtobaccoweekly

On average, how many of the following products do you smoke each day/week?

cigarsorcherootsdaily

On average, how many Cigars, cheroots, cigarillos do you smoke each day?

cigarsorcherootsweekly

On average, how many of the following products do you smoke each day/week?

shishasessionsdaily

On average, how many of the following products do you smoke each day/week?

shishasessionsweekly

On average, how many of the following products do you smoke each day/week?

othertobaccospecifydailyspec

On average, how many of the following products do you smoke each day/week?

othertobaccoweeklyspec

On average, how many of the following products do you smoke each day/week?

stopsmoking12mo

During any visit to a doctor or other health worker in the past 12 months, were

eversmoked

In the past, did you ever smoke any tobacco products?

eversmokeddaily

In the past, did you ever smoke daily?

smokecat

smokeamount

smokeamountcat

quitsmokingmonths

Quit smoking in months

quitsmokingweeks

Quit smoking in weeks

quitsmokingyears

Quit smoking in years

rememberquitsmoking

Do you remember how old you were when you last quit smoking?

everconsumedalcohol

Have you ever consumed any alcohol such as beer, wine, spirits or [add other loc

consumedalcohol12mo

Have you consumed any alcohol within the past 12 months?

stoppedalcoholhealth

Have you stopped drinking due to health reasons, such as a negative impact on yo

consumptionfrequency

During the past 12 months, how frequently have you had at least one standard alc

consumedalcohol30d

Have you consumed any alcohol within the past 30 days?

consumedalcoholoccassions

During the past 30 days, on how many occasions did you have at least one standar

drinksconsumedoccassions

During the past 30 days, when you drank alcohol, how many standard drinks on ave

drinksperoccassion

During the past 30 days, what was the largest number of standard drinks you had

sixdrinksperoccassion

During each of the past 7 days, how many standard drinks did you have each day?

lastweekmondaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

lastweektuesdaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

lastweekwednesdaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

lastweekthursdaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

lastweekfridaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

lastweeksaturdaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

lastweeksundaydrinks

During each of the past 7 days, how many standard drinks did you have each day?

consumedhomebredalcohol

During the past 7 days, did you consume any homebrewed alcohol, any alcohol brou

numberhomebredspirits

On average, how many standard drinks of the following did you consume during the

numberhomebredbeer

On average, how many standard drinks of the following did you consume during the

numberalcoholimported

On average, how many standard drinks of the following did you consume during the

numberalcoholforbidden

On average, how many standard drinks of the following did you consume during the

numberalcoholuntaxed

On average, how many standard drinks of the following did you consume during the

drinkcat

Alcohol intake category

drinkamount

Total drinks in 30 days

drinkwk

Average drinks per week

audrisk

Alcohol use disorder risk (among drinkers in past 30 days

drinkheavy

Heavy episodic drinking

agequitsmoking

Age at the time of quiting smoking

stopsmokingadvice12mo

During any visit to a doctor or other health worker in the past 12 months, were

receivedhivtestresult

Have you ever received a test result for HIV?

hadposhivresult

Have you ever had a positive HIV test result?

hadposhivresultdatetype

Do you remember the exact date, or year of your first positive test result?

hivposresult1stdate

When was your first positive test result?

hivposresult1styear

Year of First HIV Positive Result

lasthivnegresultdatetype

Type of Last HIV Negative date

lasthivnegresultdate

When was your last negative test result?

lasthivnegresultyear

Year Last HIV Negative Result

everonart

Have you ever been on ART?

artinitiationdatetype

Do you remember the exact date, or year when you first started ART?

artinitiationdate

When did you first start ART?

artinitiationyear

Year Of ART Initiation

currentlyonart

Are you currently receiving ART?

artdefault

Have you ever stopped/defaulted from ART treatment? (Defaulted explained as not

artdefaulttimes

HART default times

hivelisa

HIV Elisa Result

cd4lymphab

CD4 Lymphocytes Abs

cd4lymphpercent

CD4 Lymphocytes %

cd8lymphab

CD8 Lymphocytes Abs

cd4cd8ratio

cd8lymphpercent

CD8 Lymphocyte percent

vl

HIV Viral Load Result

vlcat

Viral load category

hivaware

Aware of HIV Status

hivcontrol

HIV positive on ART and VL <400

hivonartsupp

VL<400 among those who report being on ART

hivincare

HIV positive on ART

hivcascade

HIV care cascade status

tbtxcurrent

Are you currently on TB treatment?

receivedtbinjections

If yes, have you received injections as part of this TB treatment?

tbtxever

Have you been on TB treatment before?

numbertbtxever

If yes, how many times have you been on TB treatment?

agetbtxever

Age at TB treatment

lasttbdatecompletiontype

Do you remember the exact date, or year when you completed your last TB treatmen

lasttbdatecompletionyear

Please select the year of completion of last TB treatment

rememberagetbtxever

Do you remember how old you were when you had your FIRST diagnosis of TB?

tbinjectionsstartdate

When did you start your current treatment for TB?

tbdurationsymptoms

Duration of the symptom (weeks)

weeksagotbtxever

Ever been on TB treattment weeks ago

yearsagotbtxever

Ever been on TB treattment yearsago

lasttbdatecompletion

Date of completion of last TB treatment

homesteadmembertbever

Has anyone in your homestead (or residential plot), during your lifetime

homesteadmembertbcurr

Is anybody in your homestead (or residential plot) currently on TB treatment?

coughcurr

Do you currently have a cough?

coughduration

If yes, how long have you had the cough

coughsputum

If yes, do you cough up sputum?

fevercurr

Do you have a fever?

feverduration

If yes, how long have you had a fever?

nightsweatscurr

Do you have drenching night sweats? (Sweating at night that soaks your clothes o

nightsweatsduration

How long have you had drenching night sweats?

weightloss6mo

Have you lost weight in the last 6 months?

weightlossnumber

How much weight have you lost in the last 6 months?

othersymptoms

Do you have any other symptoms apart from those already mentioned?

tbsymptom

Any of the four TB symptoms

totaltbsymptom

Total TB symptoms

cxrscore

Chext X-Ray score

referredforsputum

Triage for sputum collection

sputumtried

Attempt to collect sputum

sputumcollected

Sputum collected

spontsputumobtained

Spontaneous specimen obtained

spontsputumnotobtained

Reason for not obtaining spontaneous specimen

inducedsputumobtained

Induced Sputum Obtained

inducedsputumnotobtained

Reason for not obtaining induced specimen

sponttbsputumhome

Spont TB SputumHome

inducedtbsputumhome

Induced TBS putum Home

genexpert

TB GeneXpert Test Result

liquidculture

Liquid Culture Result(MGIT)

rifampicin

Rifampicin Resistance

ttdculture

Time To Detection(days)

tthculture

Time To Detection(hrs)

solidincub

Solid Culture Incubation

isoniazid02

DST Isoniazid_0.2

isoniazid10

DST Isoniazid_1.0

rifampicin10

DST Rifampicin_1.0

ethambutol75

DST Ethambutol_7.5

streptomycin20

DST Streptomycin_2.0

ofloxacin20

DST Ofloxacin_2.0

kanamycin50

DST Kanamycin_5.0

tbdiagmicro

Bacteriologically confirmed TB

tbdiagmicrorx

Bacteriologically confirmed TB or on treatmen

tbcascade

TB care cascade status

bpfirstsystolic

BP First Systolic

bpfirstdiastolic

BP First Diastolic

bpsecondsystolic

BP Second Systolic

bpseconddiastolic

BP Second Diastolic

bpthirdsystolic

BP Third Systolic

bpthirddiastolic

BP Third Diastolic

bpforthsystolic

BP Forth Systolic

bpforthdiastolic

BP Forth Diastolic

meandiabp

Mean diastolic BP (2nd & 3rd)

meansysbp

Mean systolic BP (2nd & 3rd)

bpmeasuredever

Have you ever had your blood pressure measured by a doctor or other health worke

highbpinformedever

Have you ever been told by a doctor or other health worker that you have raised

highbpinformed12mo

Have you been told in the past 12 months?

highbpconsult6mo

In the past 6 months, have you seen a doctor or other health care worker about y

highbptx2wks

In the past two weeks, have you taken any drugs (medication) for raised blood pr

highbpconsulthealer

Have you ever seen a traditional healer for raised blood pressure or hypertensio

highbpherbalcurr

Are you currently taking any herbal or traditional remedy for your raised blood

bpstepsgroup

WHO STEPS BP group

bpcontrol

BP controlled with medication

bpaware

Told had raised BP by health care worker in last 12 months

bpincare

Seen health care worker in last 6m for raised BP

bprx2wk

Taken medication for raised BP in past 2 wks medication for raised BP in past 2

bpherbalrx

Taking herbal medication for raised BP

htndiag

Hypertension diagnosis (primary defn

htncascade

Hypertension care cascade status

bsugarmeasuredever

Have you ever had your blood sugar measured by a doctor or other health worker?

highbsugarinformedever

Have you ever been told by a doctor or other health worker that you have raised

highbsugarinformed12mo

Have you been told in the past 12 months?

highbsugarconsult6mo

In the past 6 months, have you seen a doctor or other health care worker about y

highbsugartx2wks

In the past two weeks, have you taken any drugs (medication) for diabetes prescr

insulintxcurr

Are you currently taking insulin for diabetes prescribed by a doctor or other he

highbsugarconsulthealer

Have you ever seen a traditional healer for diabetes or raised blood sugar?

highbsugarherbalcurr

Are you currently taking any herbal or traditional remedy for your diabetes?

hba1cpercentcat

Haemoglobin level

dmaware

Told had raised blood sugar by health care worker in last 12m

dmdiag

Diabetes diagnosis (primary definition)

dmcontrol

Diabetes controlled with medication

dmincare

Seen health care worker in last 6m for raised blood suga

dmrx2wk

Taken medication (non-insulin) for raised blood sugar in past 2 wks

dminsulin

Currently taking insulin for diabetes

cholestmeasuredever

Have you ever had your cholesterol (fat levels in your blood) measured by a doct

highcholestinformedever

Have you ever been told by a doctor or other health worker that you have raised

highcholestinformed12mo

Have you been told in the past 12 months?

highcholesttx2wks

In the past two weeks, have you taken any oral treatment (medication) for raised

dmcascade

Diabetes care cascade status

highcholestconsulthealer

Have you ever seen a traditional healer for raised cholesterol?

highcholestherbalcurr

Are you currently taking any herbal or traditional remedy for your raised choles

heartattackever

Have you ever had a heart attack or chest pain from heart disease (angina)?

heartattackaspirintxcurr

Are you currently taking aspirin regularly to prevent or treat heart disease?

heartattackstatinstxcurr

Are you currently taking statins (Lovastatin/Simvastatin/Atorvastatin or any oth

parenthistheartattack

Did your mother or father have a heart attack before the age of 60?

hadstrokeever

Have you ever had a stroke (cerebrovascular accident or incident)?

strokeaspirintxcurr

Are you currently taking aspirin regularly to prevent a stroke?

statinsstroketxcurr

Are you currently taking statins (Lovastatin/Simvastatin/Atorvastatin or any oth

parenthiststroke

Did your mother or father have a stroke before the age of 60?

cancertxever

Have you been treated for cancer before?

cancertype

bpreferallfu

Blood Pressure referral follow up

diabetesreferallfu

Diabetes referral follo

fuglucoseresult

Follow up Glucose Result

fudiabetesdiagnosis

Follow up Diabetes Diagnosis

fudiabetesclinicdate

Follow up Diabetes Clinic Date

fudiastolicbp

Follow up Diastolic BP

fubpdiagnosis

UFollow up BP Diagnosis

hba1c

hba1cpercent

Hemoglobin percent

age

RECODE of AgeAtEnrolmentCat (Age category at enrolment)

m_status

RECODE of MaritalStatus (Marital status of the individual during this episode)

smoking_advice

RECODE of StopSmokingAdvice12mo (During any visit to a doctor or other health wo

edu_cat

RECODE of Education (Education status of individual during this episode)

isurbanorrural

Is urban or rural

educ_hse

educ_socdem

entrydate

exitdate

dwt

Design weight (prob of selection)

educ_num

hbsag_clean

hbsab_clean

antihbc_clean

miss_hbsag

miss_hbsab

miss_ahbc

hbsab_result_clean

hbsab_op

anti-HBs censoring flag

hbsab_num

anti-HBs (mIU/mL), numeric (raw parsed)

hbsab_ge10

anti-HBs â‰¥10 mIU/mL

obs

Total: 295

Back to Catalog